Results

Diseminarea rezultatelor

Publicații in reviste cu factor de impact

  1. Ionescu OM, Iacob A-T, Mignon A, Van Vlierberghe S, Baican M, Danu M, Ibanescu C, Simionescu N, Profire L. Design, preparation and in vitro characterization of biomimetic and bioactive chitosan/polyethylene oxide based nanofibers as wound dressings. Int. J. Biol. Macromol. 2021, 193(Part A), 996-1008 (IF = 6,953)
  2. Tatarusanu S-M, Lupascu F-M, Profire B-S, Szilagy A, Gardikiotis I, Iacob A-T, Caluian I, Herciu L, Gîscă T-C, Baican MC, Crivoi F, Profire L. Modern Approaches in Wounds Management. Polymers 2023, 15, 3648. (IF = 5.0).
  3. Tatarusanu SM, Sava Al, Profire B-S, Pinteala T, Jitareanu A, Iacob A-T, Lupascu F, Simionescu N, Rosca I, Profire L. New Smart Bioactive and Biomimetic Chitosan-Based Hydrogels for Wounds Care Management. Pharmaceutics 2023, 15, 975 (IF = 5.4).
  4. Vasincu IM, Apotrosoaei M, Lupascu F, Iacob A-T, Giusca S-E, Caruntu I-D, Marangoci N-L, Petrovici AR, Stanciu GD, T B-I, Profire B-S, Focsa A-V, Pinteala M, Profire L. Complexes of Ibuprofen Thiazolidin-4-One Derivatives with Cyclodextrin: Characterization and In Vivo Release Profile and Biological Evaluation. Pharmaceutics 2023, 15, 2492 (IF = 5,4).

Publicații in reviste BDI

  1. Ionescu OM, Profire BS, Iacob AT, Lupașcu F, Lupașcu D, Taușer R-G, Iurascu T, Ababei A, Apotrosoaei M, Jităreanu A, Sava A, Profire L. Design and optimization method for obtaining new chitosan-based nanofibers for wound healing application. Revista Medico-Chirurgicală a Societății de Medici și Naturaliști, Iași (Med. Surg. J. – Rev. Med. Chir. Soc. Med. Nat) Iaşi 2022, 126(1): 118-125.
  2. Lupașcu F, Constantin SM, Profire BS, Vasincu I, Ionescu OM, Iacob AT, Iurascu T, Ababei A, Apotrosoaei M, Jităreanu A, Sava A, Profire L. Design and optimization method for obtaining pioglitazone and curcumin-loaded chitosan Nanoparticles. Revista Medico-Chirurgicală a Societății de Medici șiNaturaliști, Iași (Med. Surg. J. – Rev. Med. Chir. Soc. Med. Nat) Iaşi 2022, 126(1): 126-134.

Participări la manifestari stiintifice nationale/internaționale

  1. Profire L, Iacob AT, Ionescu OM, Iurașcu T, Gardikiotis I, Giusca SE, Caruntu ID. The Biomedical Applications of Chitosan Based Nanomaterials as Wound Dressings. International Scientific Conference Applications of Chemistry in Nanosciences and Biomaterials Engineering, 25-26 June 2021 (virtual conference) (plenary lecture)
  2. Ionescu OM, Iacob AT, Mignon A,. VanVlierberghe S, Iurașcu T, Gardikiotis I, Simionescu N, Profire L. Hyaluronic Acid-Based Electrospun Nanofibers: Design and Characterization. International Scientific Conference Applications of Chemistry in Nanosciences and Biomaterials Engineering,25-26 June 2021 (virtual conference) (oral communacation).
  3. Iurascu T, Iacob AT, Sava A, Ionescu OM, Profire L. New nanofibers based chitosan and active substances for the treatment of wounds. Interfacing Chemical Biology and Drug Discovery, 56th International Conference on Medicinal Chemistry, 7-9 July 2021 (virtual conference) (poster, P125).
  4. Iurașcu T, Iacob TA, Sava A, Ionescu OM, Profire L. Characterization of Novel Chitosan-Based Nanofibers for Biomedical Applications.  International Scientific Conference Applications of Chemistry in Nanosciences and Biomaterials Engineering– NanoBioMat 2021, 25-27 November 2021 (vitual conference) (oral communication).
  5. Iacob AT, Ionescu OM, Iurascu T, Apotrosoaei M, Lupascu F, Vasincu I, Sava A, Dragan M, Lupascu D, Profire L. Biomimetic Chitosan/PEO Nanofibers as Non-Cytotoxic Wound Dressings. International Scientific Conference Applications of Chemistry in Nanosciences and Biomaterials Engineering, Bucharest 22-24 June 2022 (comunicare orala) – lucrare premiată;
  6. Ionescu OM, Iacob AT, Floris F, Farci A, Hanghicel T, Gardikiotis I, Căruntu ID, Giușcă S, Profire L. Novel bioactive chitosan-peo-based nanofibers for wound healing applications: an in vivo study. International Scientific Conference Applications of Chemistry in Nanosciences and Biomaterials Engineering, Bucharest 22-24 June 2022 (comunicare orală).
  7. Ionescu OM, Iacob AT, Lupașcu Florentina, Apotrosoaei M, Drăgan M, Hanghicel T, Gardikiotis I, Căruntu SD, Giușcă S, Profire L. New bioactive hyaluronic acid-PEO-based nanofibers for wound healing applications: an in vivo study. 29th Young Research Fellows Meeting, 4-6 July 2022, School of Pharmacy Nantes, France, P 13: 77-78.
  8. Iacob AT, Ionescu OM, Lupașcu F, Apotrosoaei M, Vasincu I, Drăgan M, Sava A, Focșa A, Bîrsan M, Taușer G, Profire L. The evaluation of cell cytotoxicity through MTT assay for chitosan based electrospun nanofibrous mats as wound dressing. 29th Young Research Fellows Meeting, 4-6 July 2022, School of Pharmacy Nantes, France, P 42: 106-107.
  9. Iacob AT, Ionescu OM, Profire L. Development and biological assessment in terms of cytotoxicity and hemolytic effect of hyaluronic acid (HA) based electrospun nanofibers. COST-Workshop Fit 4 NANO, 11-13 July, Poland, Krakow.
  10. Ionescu OM, Iacob AT, Mignon A, Simionescu N, Gardikiotis I, Caruntu ID, Giusca SE, Van Vlierberghe S, Profire L. Polyethylene oxide-hyaluronic acid-based electrospun nanofibers: in vitro and in vivo studies. COST-Workshop Fit 4 NANO, 11-13 July, Poland, Krakow.
  11. Iacob A-T, Ionescu O-M, Lupașcu F, Apotrosoaei M,  Vasincu I, Focșa A, Bîrsan M, Lupașcu D, Drăgan M, Profire L. Biological assessment in terms of cytotoxicity of hyaluronic acid (HA) based electrospun nanofibers. 30th Young Research Fellows Meeting 1-3 February 2023, School of Pharmacy Paris, France P04: 94-95.
  12. Iacob A-T, Ionescu O.M., Dragan M, Lupascu F, Apotrosoaei M, Vasincu I, Profire L. The formulation and hemolytic assessment of biomimetic polysaccharide electrospun nanofibers. Fit4nano Workshop, 17th-19th July 2023, Lisbon, Portugal
  13. Ionescu OM, Iacob A, Lupascu F, Apotrosoaie M, Vasincu I, Dragan M, Profire L. A overview on the biological effects of hyaluronic acid nanofibers for wound healing applications. Fit4nano Workshop, 17th-19th July 2023, Lisbon, Portugal.
  14. Iacob A-T, Ionescu O-M, Lupascu F, Dragan M, Apotrosoaei M, Vasincu I, Profire L. Antioxidant Evaluation of biomimetic chitosan nanofibrous mats as wound dressings. GP2A- 31st Annual Medicinal Chemistry Conference – 23rd-25th August 2023, Aix-Marseille, France.
  15. Profire L. Innovative approaches in wound healing. The 37th Balkan Medical Week. The perspectives of Balkan Medicine in the post COVID-19 Era, 7-9 iunie 2023, Chisinău, Republica Moldova.

Teze doctorat finalizate

  1. Ionescu OM. Dezvoltarea și caracterizarea de noi nanofibre cu aplicații biomedicale, Conducător științific Prof. Dr. Lenuța Profire, dată susținere publică: 02.08.2023.